Stem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration

BACKGROUND: Stem cell antigen-1 (Sca-1 or Ly6A) is a glycosyl phostidylinositol (GPI)-anchored cell surface protein associated with both stem and progenitor activity, as well as tumor initiating-potential. However, at present the functional role for Sca-1 is poorly defined. METHODOLOGY/PRINCIPAL FIN...

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Bibliografiske detaljer
Main Authors: Batts, Torey D., Machado, Heather L., Zhang, Yiqun, Creighton, Chad J., Li, Yi, Rosen, Jeffrey M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226565/
https://ncbi.nlm.nih.gov/pubmed/22140470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027841
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