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Copy Number Variation of KIR Genes Influences HIV-1 Control

A genome-wide screen for large structural variants showed that a copy number variant (CNV) in the region encoding killer cell immunoglobulin-like receptors (KIR) associates with HIV-1 control as measured by plasma viral load at set point in individuals of European ancestry. This CNV encompasses the...

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Main Authors: Pelak, Kimberly, Need, Anna C., Fellay, Jacques, Shianna, Kevin V., Feng, Sheng, Urban, Thomas J., Ge, Dongliang, De Luca, Andrea, Martinez-Picado, Javier, Wolinsky, Steven M., Martinson, Jeremy J., Jamieson, Beth D., Bream, Jay H., Martin, Maureen P., Borrow, Persephone, Letvin, Norman L., McMichael, Andrew J., Haynes, Barton F., Telenti, Amalio, Carrington, Mary, Goldstein, David B., Alter, Galit
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226550/
https://ncbi.nlm.nih.gov/pubmed/22140359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001208
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