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Three-Dimensional System for the In Vitro Study of Megakaryocytes and Functional Platelet Production Using Silk-Based Vascular Tubes

Platelets are specialized cells produced by megakaryocytes in the bone marrow that represent the first defense against hemorrhage, yet they also play a pathological role in thrombosis, inflammation, and cancer. Millions of platelet transfusions are conducted each year, and the supply of this blood c...

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Bibliographic Details
Main Authors: Pallotta, Isabella, Lovett, Michael, Kaplan, David L., Balduini, Alessandra
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226422/
https://ncbi.nlm.nih.gov/pubmed/21895494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2011.0134
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