Toward a Clinical-Grade Expansion of Mesenchymal Stem Cells from Human Sources: A Microcarrier-Based Culture System Under Xeno-Free Conditions

The immunomodulatory properties of mesenchymal stem cells (MSCs) make them attractive therapeutic agents for a wide range of diseases. However, the highly demanding cell doses used in MSC clinical trials (up to millions of cells/kg patient) currently require labor intensive methods and incur high re...

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Detalhes bibliográficos
Main Authors: dos Santos, Francisco, Andrade, Pedro Z., Abecasis, Manuel M., Gimble, Jeffrey M., Chase, Lucas G., Campbell, Andrew M., Boucher, Shayne, Vemuri, Mohan C., da Silva, Cláudia Lobato, Cabral, Joaquim M.S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226421/
https://ncbi.nlm.nih.gov/pubmed/21895491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2011.0255
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