Discovery and Validation of Serum Protein Changes in Type 1 Diabetes Patients Using High Throughput Two Dimensional Liquid Chromatography-Mass Spectrometry and Immunoassays

Type 1 diabetes (T1D) is expected to cause significant changes in the serum proteome; however, few studies have systematically assessed the proteomic profile change associated with the disease. In this study, a semiquantitative spectral counting-based two dimensional liquid chromatography mass spect...

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Detalhes bibliográficos
Main Authors: Zhi, Wenbo, Sharma, Ashok, Purohit, Sharad, Miller, Eric, Bode, Bruce, Anderson, Stephen W., Reed, John Chip, Steed, R. Dennis, Steed, Leigh, Hopkins, Diane, She, Jin-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226412/
https://ncbi.nlm.nih.gov/pubmed/21900154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.012203
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