The Stability and Complexity of Antibody Responses to the Major Surface Antigen of Plasmodium falciparum Are Associated with Age in a Malaria Endemic Area

Individuals that are exposed to malaria eventually develop immunity to the disease with one possible mechanism being the gradual acquisition of antibodies to the range of parasite variant surface antigens in their local area. Major antibody targets include the large and highly polymorphic Plasmodium...

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Autori principali: Barry, Alyssa E., Trieu, Angela, Fowkes, Freya J. I, Pablo, Jozelyn, Kalantari-Dehaghi, Mina, Jasinskas, Algis, Tan, Xiaolin, Kayala, Matthew A., Tavul, Livingstone, Siba, Peter M., Day, Karen P., Baldi, Pierre, Felgner, Philip L., Doolan, Denise L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226400/
https://ncbi.nlm.nih.gov/pubmed/21825279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.008326
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