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The role of interferon in the protective effect of a synthetic double-stranded polyribonucleotide against intranasal vesicular stomatitis virus challenge in mice

Intravenous injection of polyinosinic acid/polycytidylic acid [(poly rI)·(poly rC)] offered significant protection against intranasal challenge of young mice with vesicular stomatitis virus (VSV). Optimal protection was obtained when a single dose was administered 2 hr before virus challenge, but re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Clerco, Erik De, Nuwer, Marc R., Merigan, Thomas C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1970
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC322636/
https://ncbi.nlm.nih.gov/pubmed/4317283
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