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ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease

Systemic minimal residual disease after primary tumor treatment can remain asymptomatic for decades. This is thought to be due to the presence of dormant disseminated tumor cells (DTC) or micrometastases in different organs. DTCs lodged in brain, lungs, livers, and/or bone are a major clinical probl...

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Библиографические подробности
Главные авторы: Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Bragado, Paloma, Wen, Huei-Chi, Aguirre-Ghiso, Julio A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226348/
https://ncbi.nlm.nih.gov/pubmed/21673068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2574
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