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A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C
Mutations in both acid-β-glucosidase (GCase) and saposin C lead to Gaucher disease, the most common lysosomal storage disorder. The past several years have seen an explosion of structural and biochemical information for these proteins, which have provided new insight into the biology and pathogenesi...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE-Hindawi Access to Research
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226326/ https://ncbi.nlm.nih.gov/pubmed/22145077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/973231 |
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