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Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment

The vast majority of hematopoietic stem cells (HSCs) reside in specialized niches within the bone marrow during steady state, maintaining lifelong blood cell production. A small number of HSCs normally traffic throughout the body; however, exogenous stimuli can enhance their release from the niche a...

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Autori principali: Hoggatt, Jonathan, Pelus, Louis M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226284/
https://ncbi.nlm.nih.gov/pubmed/21418553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt54
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