Detection of splicing events and multiread locations from RNA-seq data based on a geometric-tail (GT) distribution of intron length

BACKGROUND: RNA sequencing (RNA-seq) measures gene expression levels and permits splicing analysis. Many existing aligners are capable of mapping millions of sequencing reads onto a reference genome. For reads that can be mapped to multiple positions along the reference genome (multireads), these al...

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Bibliografiske detaljer
Main Authors: Lou, Shao-Ke, Li, Jing-Woei, Qin, Hao, Yim, Aldrin Kay-Yuen, Lo, Leung-Yau, Ni, Bing, Leung, Kwong-Sak, Tsui, Stephen Kwok-Wing, Chan, Ting-Fung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Proceedings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226252/
https://ncbi.nlm.nih.gov/pubmed/21988959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S5-S2
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