Synthesis and release of proinsulin and insulin by isolated rat islets of Langerhans

Isolated rat islets of Langerhans were incubated for 60, 120, and 180 min and the incorporation of leucine-(3)H into proinsulin and insulin moieties was followed. Synthesis and release of these hormones could be followed by separate extractions of islets and incubation media. Release of newly synthe...

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Publié dans:	J Clin Invest
Auteurs principaux:	Tanese, Tomio, Lazarus, Norman R., Devrim, Sevim, Recant, Lillian
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1970
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4914679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106357
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