CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

The two most common forms of inflammatory bowel disease (IBD), Crohn’s disease and ulcerative colitis, affect approximately 1 million people in the United States. Uncontrolled APC reactivity toward commensal bacteria is implicated in the pathogenesis of the disease. A number of functionally distinct...

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Main Authors: Medina-Contreras, Oscar, Geem, Duke, Laur, Oskar, Williams, Ifor R., Lira, Sergio A., Nusrat, Asma, Parkos, Charles A., Denning, Timothy L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226003/
https://ncbi.nlm.nih.gov/pubmed/22045567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59150
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