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The Riboflavin analog roseoflavin targets an FMN-riboswitch and blocks Listeria monocytogenes growth, but also stimulates virulence gene-expression and infection

During recent years, riboswitches have emerged as potential targets for novel antibacterial substances. In this study, we investigated how one flavin analog, roseoflavin, affected the gene-expression, growth and infectivity of the human bacterial pathogen Listeria monocytogenes to determine the pote...

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Detalhes bibliográficos
Main Authors: Mansjö, Mikael, Johansson, Jörgen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225981/
https://ncbi.nlm.nih.gov/pubmed/21593602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.4.15586
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