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Store-Operated Calcium Channels: New Perspectives on Mechanism and Function

Store-operated calcium channels (SOCs) are a nearly ubiquitous Ca(2+) entry pathway stimulated by numerous cell surface receptors via the reduction of Ca(2+) concentration in the ER. The discovery of STIM proteins as ER Ca(2+) sensors and Orai proteins as structural components of the Ca(2+) release-...

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Detalles Bibliográficos
Autor principal: Lewis, Richard S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225942/
https://ncbi.nlm.nih.gov/pubmed/21791698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a003970
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