Synthesis and α-Glucosidase Inhibitory Mechanisms of Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Potential Marine Bromophenol α-Glucosidase Inhibitor

Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE), derived from the marine algae, is a potential α-glucosidase inhibitor for type 2 diabetes treatment. In the present study, a synthetic route was established as a valid approach to obtain BDDE. Fluorescence spectra, circular dichroism spectra and mol...

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Bibliographic Details
Main Authors: Liu, Ming, Zhang, Wei, Wei, Jianteng, Lin, Xiukun
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225935/
https://ncbi.nlm.nih.gov/pubmed/22131958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md9091554
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