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Total syntheses of isonaamine C and isonaamidine E

The total syntheses of two alkaloids isolated from a marine sponge of the Leucetta sp. have been accomplished in 6 and 7 steps starting from a 4,5-diiodoimidazole derivative. Grignard mediated halogen-metal exchange was used to install the benzyl side chain. C2 substitution was accomplished via lith...

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Autors principals: Lima, Heather M., Garcia-Barboza, Beatriz J., Khatibi, Nicole N., Lovely, Carl J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225899/
https://ncbi.nlm.nih.gov/pubmed/22140280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.08.030
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