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Detecting variable (V), diversity (D) and joining (J) gene segment recombination using a two-colour fluorescence system

BACKGROUND: Diversity of immunoglobulins and the T cell antigen receptors is achieved via the recombination activating gene (RAG)-mediated rearrangement of variable (V), diversity (D) and joining (J) gene segments, and this underpins the efficient recognition of a seemingly limitless array of antige...

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Main Authors: Scott, Gina B, de Wynter, Erika A, Cook, Graham P
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225881/
https://ncbi.nlm.nih.gov/pubmed/20226006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-1-9
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