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RT-SVR+q: A Strategy for Post-Mascot Analysis Using Retention Time and q Value Metric to Improve Peptide and Protein Identifications
Shotgun proteomics commonly utilizes database search like Mascot to identify proteins from tandem MS/MS spectra. False discovery rate (FDR) is often used to assess the confidence of peptide identifications. However, a widely accepted FDR of 1% sacrifices the sensitivity of peptide identification whi...
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Hoofdauteurs: | , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225640/ https://ncbi.nlm.nih.gov/pubmed/21888997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.08.013 |
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