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RT-SVR+q: A Strategy for Post-Mascot Analysis Using Retention Time and q Value Metric to Improve Peptide and Protein Identifications

Shotgun proteomics commonly utilizes database search like Mascot to identify proteins from tandem MS/MS spectra. False discovery rate (FDR) is often used to assess the confidence of peptide identifications. However, a widely accepted FDR of 1% sacrifices the sensitivity of peptide identification whi...

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Bibliografische gegevens
Hoofdauteurs: Cao, Weifeng, Ma, Di, Kapur, Arvinder, Patankar, Manish S, Ma, Yadi, Li, Lingjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225640/
https://ncbi.nlm.nih.gov/pubmed/21888997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.08.013
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