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Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington’s disease provides in vivo evidence for impaired energy metabolism

Huntington’s disease (HD) is a neurodegenerative genetic disorder that affects the brain. Atrophy of deep grey matter structures has been reported and it is likely that underlying pathologic processes occur before, or in concurrence with, volumetric changes. Measurement of metabolite concentrations...

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Detalhes bibliográficos
Main Authors: van den Bogaard, Simon J. A., Dumas, Eve M., Teeuwisse, Wouter M., Kan, Hermien E., Webb, Andrew, Roos, Raymund A. C., van der Grond, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225625/
https://ncbi.nlm.nih.gov/pubmed/21614431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-011-6099-5
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