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Oxycellulose Beads with Drug Exhibiting pH-Dependent Solubility

The aim of this study was to develop novel hydrogel-based beads and characterize their potential to deliver and release a drug exhibiting pH-dependent solubility into distal parts of gastrointestinal (GI) tract. Oxycellulose beads containing diclofenac sodium as a model drug were prepared by the ion...

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Main Authors: Bajerová, Martina, Krejčová, Kateřina, Rabišková, Miloslava, Muselík, Jan, Dvořáčková, Kateřina, Gajdziok, Jan, Masteiková, Ruta
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225546/
https://ncbi.nlm.nih.gov/pubmed/22005954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9696-9
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