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Silymarin Glyceryl Monooleate/Poloxamer 407 Liquid Crystalline Matrices: Physical Characterization and Enhanced Oral Bioavailability

Silymarin, a mixture of flavonolignans extracted from the seeds of milk thistle, is used clinically as a hepatoprotector to treat liver injuries and chronic hepatitis. However, its therapeutic effect is compromised by its poor oral bioavailability due to the poor solubility and low permeability acro...

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מידע ביבליוגרפי
Main Authors: Lian, Ruyue, Lu, Yi, Qi, Jianping, Tan, Yanan, Niu, Mengmeng, Guan, Peipei, Hu, Fuqiang, Wu, Wei
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225519/
https://ncbi.nlm.nih.gov/pubmed/21948306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9666-2
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