Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction

Quantitative trait locus mapping of chemical/inflammatory pain in the mouse identified the Avpr1a gene, encoding the vasopressin-1A receptor (V1AR), as responsible for strain-dependent pain sensitivity to formalin and capsaicin. A genetic association study in humans revealed the influence of a singl...

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Main Authors: Mogil, Jeffrey S., Sorge, Robert E., LaCroix-Fralish, Michael L., Smith, Shad B., Fortin, Anny, Sotocinal, Susana G., Ritchie, Jennifer, Austin, Jean-Sebastien, Schorscher-Petcu, Ara, Melmed, Kara, Czerminski, Jan, Bittong, Rosalie A., Mokris, J. Brad, Neubert, John K., Campbell, Claudia M., Edwards, Robert R., Campbell, James N., Crawley, Jacqueline N., Lariviere, William R., Wallace, Margaret R., Sternberg, Wendy F., Balaban, Carey D., Belfer, Inna, Fillingim, Roger B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225498/
https://ncbi.nlm.nih.gov/pubmed/22019732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2941
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