Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction

Quantitative trait locus mapping of chemical/inflammatory pain in the mouse identified the Avpr1a gene, encoding the vasopressin-1A receptor (V1AR), as responsible for strain-dependent pain sensitivity to formalin and capsaicin. A genetic association study in humans revealed the influence of a singl...

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Detalhes bibliográficos
Main Authors: Mogil, Jeffrey S., Sorge, Robert E., LaCroix-Fralish, Michael L., Smith, Shad B., Fortin, Anny, Sotocinal, Susana G., Ritchie, Jennifer, Austin, Jean-Sebastien, Schorscher-Petcu, Ara, Melmed, Kara, Czerminski, Jan, Bittong, Rosalie A., Mokris, J. Brad, Neubert, John K., Campbell, Claudia M., Edwards, Robert R., Campbell, James N., Crawley, Jacqueline N., Lariviere, William R., Wallace, Margaret R., Sternberg, Wendy F., Balaban, Carey D., Belfer, Inna, Fillingim, Roger B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225498/
https://ncbi.nlm.nih.gov/pubmed/22019732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2941
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