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Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy
The genetic basis of oculopharyngeal muscular dystrophy (OPMD) is a short expansion of a polyalanine tract (normal allele: 10 alanines, mutant allele: 11–17 alanines) in the nuclear polyadenylate binding protein PABPN1 which is essential for controlling poly(A) tail length in messenger RNA. Mutant P...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225492/ https://ncbi.nlm.nih.gov/pubmed/21964252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.09.010 |
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