Effect of route of delivery on heterologous protection against HCV induced by an adenovirus vector carrying HCV structural genes

BACKGROUND: An effective vaccine and new therapeutic methods for hepatitis C virus (HCV) are needed, and a potent HCV vaccine must induce robust and sustained cellular-mediated immunity (CMI). Research has indicated that adenoviral and vaccinia vectors may have the ability to elicit strong B and T c...

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Main Authors: Guan, Jie, Wen, Bo, Deng, Yao, Zhang, Ke, Chen, Hong, Wu, Xiaobing, Ruan, Li, Tan, Wenjie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225406/
https://ncbi.nlm.nih.gov/pubmed/22054309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-506
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