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Fibronectin Protects from Excessive Liver Fibrosis by Modulating the Availability of and Responsiveness of Stellate Cells to Active TGF-β

Fibrotic tissue in the liver is mainly composed of collagen. Fibronectin, which is also present in fibrotic matrices, is required for collagen matrix assembly in vitro. It also modulates the amount of growth factors and their release from the matrix. We therefore examined the effects of the absence...

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Detalhes bibliográficos
Main Authors: Kawelke, Nina, Vasel, Matthaeus, Sens, Carla, von Au, Anja, Dooley, Steven, Nakchbandi, Inaam A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225392/
https://ncbi.nlm.nih.gov/pubmed/22140539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028181
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