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Chromosome 17: Association of a large inversion polymorphism with corticosteroid response in asthma

A 900-KB inversion exists within a large region of conserved linkage disequilibrium (LD) on chromosome 17. CRHR1 is located within the inversion region and associated with inhaled corticosteroid response in asthma. We hypothesized that CRHR1 variants are in LD with the inversion, supporting a potent...

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Autori principali: Tantisira, Kelan G., Lazarus, Ross, Litonjua, Augusto A., Klanderman, Barbara, Weiss, Scott T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225071/
https://ncbi.nlm.nih.gov/pubmed/18622266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282fe6ebf
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