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Induction of rat liver alkaline phosphatase: the mechanism of the serum elevation in bile duct obstruction

Bile duct ligation in the rat leads to a rapid increase in hepatic and serum alkaline phosphatase activity. Within 12 hr after bile duct ligation, hepatic alkaline phosphatase has increased 7-fold and serum alkaline phosphatase activity 2½-fold. The elevation in the serum activity is completely due...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Kaplan, Marshall M., Righetti, Adriana
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1970
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322498/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5415676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106260
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