Elevated pressure downregulates ZO-1 expression and disrupts cytoskeleton and focal adhesion in human trabecular meshwork cells

PURPOSE: To investigate the effect of elevated hydrostatic pressure on the expression and distribution of zonula occludens-1 (ZO-1), and its effect on cytoskeleton and focal adhesion in immortal human trabecular meshwork cells (iHTM) and glaucomatous human trabecular meshwork cells (GTM(3)). METHODS...

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Autores principales: Yang, Xuejiao, Liu, Bingqian, Bai, Yujing, Chen, Min, Li, Yiqing, Chen, Mengfei, Wei, Yantao, Ge, Jian, Zhuo, Yehong
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Vision 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224831/
https://ncbi.nlm.nih.gov/pubmed/22128243
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