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Large-Scale Candidate Gene Analysis in Whites and African-Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation: The NHLBI CARe Project

BACKGROUND: The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated. METHODS AND RESULTS: We examined a panel of approximately 50,000 common single nucleotide polymorphisms (SNPs...

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Detalhes bibliográficos
Main Authors: Schnabel, Renate B., Kerr, Kathleen F., Lubitz, Steven A., Alkylbekova, Ermeg L., Marcus, Gregory M., Sinner, Moritz F., Magnani, Jared W., Wolf, Philip A., Deo, Rajat, Lloyd-Jones, Donald M., Lunetta, Kathryn L., Mehra, Reena, Levy, Daniel, Fox, Ervin R., Arking, Dan E., Mosley, Thomas H., Mueller, Martina, Young, Taylor, Wichmann, Erich, Seshadri, Sudha, Farlow, Deborah N., Rotter, Jerome I., Soliman, Elsayed Z., Glazer, Nicole L., Wilson, James G., Breteler, Monique M.B., Sotoodehnia, Nona, Newton-Cheh, Christopher, Kääb, Stefan, Ellinor, Patrick T., Alonso, Alvaro, Benjamin, Emelia J., Heckbert, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224824/
https://ncbi.nlm.nih.gov/pubmed/21846873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.110.959197
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