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The effects of deoxygenation of adult and fetal hemoglobin on the synthesis of red cell 2,3-diphosphoglycerate and its in vivo consequences

Patients over 1 month of age with arterial oxygen pressures of less than 60 mm Hg were found to have elevated red cell 2,3-diphosphoglycerate (2,3-DPG) levels and blood with a decreased affinity for oxygen. The increase in 2,3-DPG was proportional to the degree of hypoxemia. In patients under 1 mont...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Oski, Frank A., Gottlieb, Arlan J., Miller, William W., Delivoria-Papadopoulos, Maria
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1970
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5411790/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106249
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