Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation

BACKGROUND: Radix ophiopogonis polysaccharide (ROP) has been found to be effective against myocardial ischemia. One of main problems with its use is its short in-vivo half-life, which makes the development of an effective delivery system necessary. To achieve better therapeutic effects and patient c...

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Bibliographic Details
Main Authors: Lin, Xiao, Wang, Zhuo-Jun, Huang, Fang, Liang, Shuang, Shen, Lan, Feng, Yi, Ruan, Ke-Feng
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2011
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224713/
https://ncbi.nlm.nih.gov/pubmed/22131832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S26306
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