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Amorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effects

BACKGROUND: The purpose of this study was to investigate the mechanism of noxious effects of amorphous silica nanoparticles on human endothelial cells. METHODS: Nanoparticle uptake was examined by transmission electron microscopy. Electrochemical nanosensors were used to measure the nitric oxide (NO...

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Main Authors: Corbalan, J Jose, Medina, Carlos, Jacoby, Adam, Malinski, Tadeusz, Radomski, Marek W
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224709/
https://ncbi.nlm.nih.gov/pubmed/22131828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25071
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