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A novel point mutation within the EDA gene causes an exon dropping in mature RNA in Holstein Friesian cattle breed affected by X-linked anhidrotic ectodermal dysplasia

BACKGROUND: X-linked anhidrotic ectodermal dysplasia is a disorder characterized by abnormal development of tissues and organs of ectodermal origin caused by mutations in the EDA gene. The bovine EDA gene encodes the ectodysplasin A, a membrane protein expressed in keratinocytes, hair follicles and...

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Main Authors: Gargani, Maria, Valentini, Alessio, Pariset, Lorraine
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224562/
https://ncbi.nlm.nih.gov/pubmed/21740563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-7-35
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