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Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor

BACKGROUND: Streptomyces coelicolor, a model organism of antibiotic producing bacteria, has one of the largest genomes of the bacterial kingdom, including 7825 predicted protein coding genes. A large number of these genes, nearly 34%, are functionally orphan (hypothetical proteins with unknown funct...

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Autores principales: Alam, Mohammad Tauqeer, Takano, Eriko, Breitling, Rainer
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224560/
https://ncbi.nlm.nih.gov/pubmed/21899768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-325
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