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Failure of Nitro Blue Tetrazolium reduction in the phagocytic vacuoles of leukocytes in chronic granulomatous disease

The leukocytes of patients with chronic granulomatous disease (CGD) may be identified by their failure to reduce Nitro Blue Tetrazolium (NBT) during phagocytosis. This reaction, normally detected in the phagocytic vacuole, is absent or delayed in CGD monocytes and eosinophils as well as in neutrophi...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Nathan, David G., Baehner, Robert L., Weaver, Don K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1969
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5387730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106156
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