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Improving probe set selection for microbial community analysis by leveraging taxonomic information of training sequences

BACKGROUND: Population levels of microbial phylotypes can be examined using a hybridization-based method that utilizes a small set of computationally-designed DNA probes targeted to a gene common to all. Our previous algorithm attempts to select a set of probes such that each training sequence manif...

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Main Authors: Ruegger, Paul M, Della Vedova, Gianluca, Jiang, Tao, Borneman, James
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224148/
https://ncbi.nlm.nih.gov/pubmed/21985453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-394
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