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Assessing pooled BAC and whole genome shotgun strategies for assembly of complex genomes

BACKGROUND: We investigate if pooling BAC clones and sequencing the pools can provide for more accurate assembly of genome sequences than the "whole genome shotgun" (WGS) approach. Furthermore, we quantify this accuracy increase. We compare the pooled BAC and WGS approaches using in silico...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Haiminen, Niina, Feltus, F Alex, Parida, Laxmi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224119/
https://ncbi.nlm.nih.gov/pubmed/21496274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-194
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