QTc prolongation assessment in anticancer drug development: clinical and methodological issues

Cardiac safety assessments are commonly employed in the clinical development of investigational oncology medications. In anti-cancer drug development there has been increasing consideration for the potential of a compound to cause adverse electrocardiographic changes, especially QT interval prolonga...

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Detalhes bibliográficos
Main Authors: Curigliano, G, Spitaleri, G, de Braud, F, Cardinale, D, Cipolla, C, Civelli, M, Colombo, N, Colombo, A, Locatelli, M, Goldhirsch, A
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2009
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Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223992/
https://ncbi.nlm.nih.gov/pubmed/22275999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2009.130
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