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Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

Chronic venous disease and venous hypertension are common consequences of valve insufficiency, yet the molecular mechanisms regulating the formation and maintenance of venous valves have not been studied. Here, we provide what we believe to be the first description of venous valve morphogenesis and...

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Autors principals: Bazigou, Eleni, Lyons, Oliver T.A., Smith, Alberto, Venn, Graham E., Cope, Celia, Brown, Nigel A., Makinen, Taija
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223924/
https://ncbi.nlm.nih.gov/pubmed/21765212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58050
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