Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations

BACKGROUND: Linear regression models are used to quantitatively predict drug resistance, the phenotype, from the HIV-1 viral genotype. As new antiretroviral drugs become available, new resistance pathways emerge and the number of resistance associated mutations continues to increase. To accurately i...

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Main Authors: Van der Borght, Koen, Van Craenenbroeck, Elke, Lecocq, Pierre, Van Houtte, Margriet, Van Kerckhove, Barbara, Bacheler, Lee, Verbeke, Geert, van Vlijmen, Herman
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223907/
https://ncbi.nlm.nih.gov/pubmed/21966893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-386
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