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Estimating developmental states of tumors and normal tissues using a linear time-ordered model

BACKGROUND: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic development and stem cell differentiation are ordered processes in which the sequence of events over time is highly conserved. The...

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Detalhes bibliográficos
Main Authors: Zhang, Bo, Chen, Beibei, Wu, Tao, Xuan, Zhenyu, Zhu, Xiaopeng, Chen, Runsheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223864/
https://ncbi.nlm.nih.gov/pubmed/21310084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-53
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