WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells

Cannabinoid receptors 1 (CB1) and/or 2 (CB2) are overexpressed in many types of human malignancies including mantle cell lymphoma (MCL). Agonists to CB1 and CB2 promote ceramide de novo synthesis, p38–mitogen-activated protein kinase-dependent activation of caspase-3 and apoptotic cell death in most...

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Detalhes bibliográficos
Main Authors: Wasik, A M, Almestrand, S, Wang, X, Hultenby, K, Dackland, Å-L, Andersson, P, Kimby, E, Christensson, B, Sander, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223692/
https://ncbi.nlm.nih.gov/pubmed/22048168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.106
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