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Impact of epistasis and pleiotropy on evolutionary adaptation

Evolutionary adaptation is often likened to climbing a hill or peak. While this process is simple for fitness landscapes where mutations are independent, the interaction between mutations (epistasis) as well as mutations at loci that affect more than one trait (pleiotropy) are crucial in complex and...

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Detalhes bibliográficos
Main Authors: Østman, Bjørn, Hintze, Arend, Adami, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223680/
https://ncbi.nlm.nih.gov/pubmed/21697174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.0870
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