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A Novel Topoisomerase Inhibitor, Daurinol, Suppresses Growth of HCT116 Cells with Low Hematological Toxicity Compared to Etoposide

We report that daurinol, a novel arylnaphthalene lignan, is a promising potential anticancer agent with adverse effects that are less severe than those of etoposide, a clinical anticancer agent. Despite its potent antitumor activity, clinical use of etoposide is limited because of its adverse effect...

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Detalhes bibliográficos
Main Authors: Kang, Kyungsu, Oh, Seung Hyun, Yun, Ji Ho, Jho, Eun Hye, Kang, Ju-Hee, Batsuren, Dulamjav, Tunsag, Jigjidsuren, Park, Kwang Hwa, Kim, Minkyun, Nho, Chu Won
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223608/
https://ncbi.nlm.nih.gov/pubmed/22131880
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