A Novel Topoisomerase Inhibitor, Daurinol, Suppresses Growth of HCT116 Cells with Low Hematological Toxicity Compared to Etoposide

We report that daurinol, a novel arylnaphthalene lignan, is a promising potential anticancer agent with adverse effects that are less severe than those of etoposide, a clinical anticancer agent. Despite its potent antitumor activity, clinical use of etoposide is limited because of its adverse effect...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kang, Kyungsu, Oh, Seung Hyun, Yun, Ji Ho, Jho, Eun Hye, Kang, Ju-Hee, Batsuren, Dulamjav, Tunsag, Jigjidsuren, Park, Kwang Hwa, Kim, Minkyun, Nho, Chu Won
التنسيق: Artigo
اللغة:Inglês
منشور في: Neoplasia Press Inc. 2011
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223608/
https://ncbi.nlm.nih.gov/pubmed/22131880
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