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PubChem3D: Biologically relevant 3-D similarity

BACKGROUND: The use of 3-D similarity techniques in the analysis of biological data and virtual screening is pervasive, but what is a biologically meaningful 3-D similarity value? Can one find statistically significant separation between "active/active" and "active/inactive" spac...

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Bibliografske podrobnosti
Main Authors: Kim, Sunghwan, Bolton, Evan E, Bryant, Stephen H
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223603/
https://ncbi.nlm.nih.gov/pubmed/21781288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-3-26
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