Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β

BACKGROUND: Microglia and astrocytes respond to homeostatic disturbances with profound changes of gene expression. This response, known as glial activation or neuroinflammation, can be detrimental to the surrounding tissue. The transcription factor CCAAT/enhancer binding protein β (C/EBPβ) is an imp...

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Detalhes bibliográficos
Main Authors: Straccia, Marco, Gresa-Arribas, Núria, Dentesano, Guido, Ejarque-Ortiz, Aroa, Tusell, Josep M, Serratosa, Joan, Solà, Carme, Saura, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223504/
https://ncbi.nlm.nih.gov/pubmed/22074460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-156
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