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Detection of β cell death in diabetes using differentially methylated circulating DNA
In diabetes mellitus, β cell destruction is largely silent and can be detected only after significant loss of insulin secretion capacity. We have developed a method for detecting β cell death in vivo by amplifying and measuring the proportion of insulin 1 DNA from β cells in the serum. By using prim...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223447/ https://ncbi.nlm.nih.gov/pubmed/22074781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111008108 |
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