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Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-β1 therapies in inducible nitric oxide synthase-deficient mice

OBJECTIVES: To investigate whether sustained long-term separate treatments of diabetic inducible nitric oxide synthase knockout (iNOSKo) mice with allopurinol, an antioxidant inhibiting xanthine oxidoreductase, decorin, a transforming growth factor-β1 (TGFβ1) -binding antagonist, and molsidomine, a...

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Detalhes bibliográficos
Main Authors: Ferrini, Monica G., Moon, Joanne, Rivera, Steve, Rajfer, Jacob, Gonzalez-Cadavid, Nestor F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223318/
https://ncbi.nlm.nih.gov/pubmed/21851542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2011.10397.x
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