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Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors
Glioblastoma multiforme (GBM) is a highly malignant brain tumor with an average survival time of 15 months. Previously, we and others demonstrated that CD4(+)FoxP3(+) regulatory T cells (Tregs) infiltrate human GBM as well as mouse models that recapitulate malignant brain tumors. However, whether br...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223094/ https://ncbi.nlm.nih.gov/pubmed/21908444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor134 |
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