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Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors

Glioblastoma multiforme (GBM) is a highly malignant brain tumor with an average survival time of 15 months. Previously, we and others demonstrated that CD4(+)FoxP3(+) regulatory T cells (Tregs) infiltrate human GBM as well as mouse models that recapitulate malignant brain tumors. However, whether br...

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Библиографические подробности
Главные авторы: Wainwright, Derek A., Sengupta, Sadhak, Han, Yu, Lesniak, Maciej S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223094/
https://ncbi.nlm.nih.gov/pubmed/21908444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor134
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